Test Overview
Method
Kinetic interaction of microparticles in solution immunoassay (KIMS)
Analytical Platform
Roche cobas 6000
Result Included
Amikacin
Aliases/Synonyms
Aminoglycoside
Specimen
Specimen Type
Avoid gel separator tubesSerum
Containers
Collection Containers
Red top (no additive)
Volume
Sample Volume
1 mL
Minimum Volume
0.5 mL
Collection & Handling
Collection Instructions
Avoid gel-separator tubes.
For traditional dosing, collect sample 30 minutes after end of dose infusion. Wait until the third dose before collecting samples for therapeutic monitoring.
For extended dosing, after the third dose collect a sample 8 – 12 hours after end of dose infusion. Record the exact time of sampling and use nomogram for dosage adjustment if necessary.
Handling Information
Separate samples from cells as soon as possible. Repeated freezing and thawing of samples should be avoided
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 4 hours | 7 days | 14 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Gel separator tube |
| Hemolysis | Present |
| Icterus | Present |
Performance & Interpretation
Turnaround Time
1 Day
Results
Name
Units
Reference Range
Conversion
-
Amikacin - Randommg/LFor traditonal (conventional) dosing method in adults:
Pre-dose < 8 mg/L
Half-hour post dose 20 - 30 mg/L
For urinary tract infections: 15 -30 mg/L
For extended interval (once daily) dosing method in adults:
Pre-dose <1.0 mg/L
8 - 12 hours post dose:Use nomogram for interpretation.
Comment
Refer to guidelines for Aminoglycoside dosing at your institution.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| AMIKR | Amikacin | 5850 | mg/L |
Test Version
Last Updated
2023-03-02