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Perampanel LC-MS/MS, Serum/Plasma
Test ID: PERAM
Test
Aliases/Synonyms
Method
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Report Includes
Perampanel
Specimens
Avoid gel-separator tubes; Serum; Plasma
Test Location
NMS Labs, Pennsylvania USA
Test Version
26-Jan-2023
Specimen
Specimens
Avoid gel-separator tubes; Serum; Plasma
Collection Containers
Preferred
Red top (no additive)
Acceptable
Lavender top (EDTA)
Sample Volume
1 ml
Minimum Volume
0.3 mL
Specimen Comment
Avoid gel separator tubes
Collection & Handling
Collection Instructions
Promptly centrifuge and separate serum or plasma into a transport tube.
Stability
| Ambient | 30 days |
|---|---|
| Refrigerated | 30 days |
| Frozen | 25 months |
Rejection Criteria
| Specimen | Gel-separator tubes |
|---|
Test Version
26-Jan-2023
Performance / Interpretation
Method
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Turnaround Time
15 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Perampanel | ng/mL |
|
||
|
Daily administration of 6 mg perampanel resulted in peak plasma concentrations averaging 460 ng/mL at approximately 1.3 hours post dose. Peak concentrations following a single 12 mg dose of perampanel averaged 800 ng/mL.
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Test Location
NMS Labs, Pennsylvania USA
Test Version
26-Jan-2023
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| PERAM | 62060PERAMPANEL, SERUM/PLASMA | ng/mL |
Test Version
26-Jan-2023