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Back to Test Catalogue
Test ID: HEVAB S

Hepatitis E Virus (HEV) Antibodies IgG and IgM, Serum

Test Overview

Clinical Utility

Hepatitis E virus (HEV) is the major etiologic agent of enterically transmitted non-A, non-B hepatitis worldwide and has a high case-fatality rate in pregnant women. Both IgM and IgG antibody to HEV (anti-HEV) are produced following infection. The titer of IgM anti-HEV declines rapidly during early convalescence; IgG anti-HEV persists and appears to provide at least short-term protection against disease.

Method

Enzyme-linked immunosorbent assay (ELISA)

Result Included

HEV IgG; HEV IgM

Specimen

Specimen Type

Serum

Containers

Collection Containers

Gold top (clot activator & gel)

Volume

Sample Volume

1 mL

Minimum Volume

0.2 mL

Collection & Handling

Handling Information

Store and send cold or frozen.

Stability

Ambient Refrigerated Frozen
7 days 14 days 30 days

Performance & Interpretation

Turnaround Time

10 days

Results

Name
Units
Reference Range
Conversion
  1. HEV IgG
    Not detected
  2. HEV IgM
    Not Detected

    Comment

    Hepatitis E virus (HEV) is a major cause of enteric non-A hepatitis worldwide. Both HEV IgM and IgG are typically detected within one month after infection; IgM persists for about two months, whereas IgG levels persist for months to years after recovery. Approximately 20% of the US population is positive for HEV IgG, indicating that HEV exposure is more common than previously thought.

Referral Location

Out-of-Country

Interface & Setup

HL7 Interface Codes

Order Code Result Name Result Codes Units
HEVAB HEV IGG 63055
HEV IGM 63056

Test Version

Last Updated

2023-03-01