Vanillylmandellic Acid (VMA) LC-MS/MS, Random Urine
Orderable by Ontario ND
Test Overview
Method
Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Result Included
VMA; VMA/Creat Ratio; Creatinine
Specimen
Specimen Type
Urine (Random)Containers
Collection Containers
Mid-stream urine container
Volume
Sample Volume
5 mL
Minimum Volume
2 mL
Patient Preparation
The following foods and medications should be avoided for three (3) days prior to the collection of urine, and during the collection of the sample:
Foods containing high caffeine concentrations (e.g. coffee, tea, cocoa, chocolate, caffeinated beverages, foods containing high amine concentrations (e.g. bananas, avocados, cheese, walnuts, alcohol, fruit and juices) and foods containing vanilla can increase urinary HVA/VMA excretion. Essential hypertension, intense anxiety and intense physical exercise can also result in raised HVA/VMA excretion.
Medications and drugs such as Salicylate, Histamine, Acetaminophen, Levodopa, Ajmaline, Lithium, Epinephrine, Nitroglycerin, Glucagon, Rauwolfia Alkaloids and Guanethidine can increase HVA/VMA.
Contact your physician for approval before discontinuing any prescription medication. Be sure to discuss all non-prescription medications with your physician.
Collection & Handling
Handling Information
Aliquot 2 mL of urine from the random collection sample and adjust pH to 2 – 4 with Hydrochloric acid.
Stability
| Refrigerated | Frozen |
|---|---|
| 1 month | 90 days |
Performance & Interpretation
Turnaround Time
8 days
Results
-
VMA/Creat Ratioµmol/mmol cr< 2: ≤ 11.0
2 - 5 y: ≤ 6.5
5 - < 20 y: ≤ 5.0
≥ 20 y: ≤ 4.0
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| VMARU | Creatinine Rand Urine | 28004 | mmol/L |
| VMA Random | 28078 | umol/L | |
| VMA/Create Ratio Random | 28080 | umol/mmol creatinine |
Test Version
Last Updated
2022-11-16