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Back to Test Catalogue
Test ID: VMARU

Vanillylmandellic Acid (VMA) LC-MS/MS, Random Urine

Orderable by Ontario ND

Test Overview

Method

Liquid chromatography-tandem mass spectrometry (LC-MS/MS)

Result Included

VMA; VMA/Creat Ratio; Creatinine

Specimen

Specimen Type

Urine (Random)

Containers

Collection Containers

Mid-stream urine container

Volume

Sample Volume

5 mL

Minimum Volume

2 mL

Patient Preparation

The following foods and medications should be avoided for three (3) days prior to the collection of urine, and during the collection of the sample:
Foods containing high caffeine concentrations (e.g. coffee, tea, cocoa, chocolate, caffeinated beverages, foods containing high amine concentrations (e.g. bananas, avocados, cheese, walnuts, alcohol, fruit and juices) and foods containing vanilla can increase urinary HVA/VMA excretion. Essential hypertension, intense anxiety and intense physical exercise can also result in raised HVA/VMA excretion.
Medications and drugs such as Salicylate, Histamine, Acetaminophen, Levodopa, Ajmaline, Lithium, Epinephrine, Nitroglycerin, Glucagon, Rauwolfia Alkaloids and Guanethidine can increase HVA/VMA.
Contact your physician for approval before discontinuing any prescription medication. Be sure to discuss all non-prescription medications with your physician.

Collection & Handling

Handling Information

Aliquot 2 mL of urine from the random collection sample and adjust pH to 2 – 4 with Hydrochloric acid.

Stability

Refrigerated Frozen
1 month 90 days

Performance & Interpretation

Turnaround Time

8 days

Results

Name
Units
Reference Range
Conversion
  1. VMA/Creat Ratio
    µmol/mmol cr
    < 2: ≤ 11.0
    2 - 5 y: ≤ 6.5
    5 - < 20 y: ≤ 5.0
    ≥ 20 y: ≤ 4.0

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code Result Name Result Codes Units
VMARU Creatinine Rand Urine 28004 mmol/L
VMA Random 28078 umol/L
VMA/Create Ratio Random 28080 umol/mmol creatinine

Test Version

Last Updated

2022-11-16