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Vanillylmandellic Acid (VMA) LC-MS/MS, Random Urine

Test ID: VMARU
Orderable by Ontario ND

Test

Method

LC-MS/MS

Report Includes

VMA; VMA/Creat Ratio; Creatinine

Specimens

Urine (Random)

Test Location

St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8

Test Version

16-Nov-2022

Specimen

Specimens

Urine (Random)

Collection Containers

Mid-stream urine container

Sample Volume

5 mL

Minimum Volume

2 mL

Patient Preparation

The following foods and medications should be avoided for three (3) days prior to the collection of urine, and during the collection of the sample:
Foods containing high caffeine concentrations (e.g. coffee, tea, cocoa, chocolate, caffeinated beverages, foods containing high amine concentrations (e.g. bananas, avocados, cheese, walnuts, alcohol, fruit and juices) and foods containing vanilla can increase urinary HVA/VMA excretion. Essential hypertension, intense anxiety and intense physical exercise can also result in raised HVA/VMA excretion.
Medications and drugs such as Salicylate, Histamine, Acetaminophen, Levodopa, Ajmaline, Lithium, Epinephrine, Nitroglycerin, Glucagon, Rauwolfia Alkaloids and Guanethidine can increase HVA/VMA.
Contact your physician for approval before discontinuing any prescription medication. Be sure to discuss all non-prescription medications with your physician.

Collection & Handling

Handling Information

Aliquot 2 mL of urine from the random collection sample and adjust pH to 2 – 4 with Hydrochloric acid.

Stability

Refrigerated 1 month
Frozen 90 days

Test Version

16-Nov-2022

Performance / Interpretation

Method

LC-MS/MS

Turnaround Time

8 days

Results

Name Units Reference Range Conversion Factor
VMA/Creat Ratio µmol/mmol cr
  • < 2: ≤ 11.0
  • 2 - 5 y: ≤ 6.5
  • 5 - < 20 y: ≤ 5.0
  • ≥ 20 y: ≤ 4.0

Test Location

St. Michael's Hospital, 30 Bond Street, Toronto ON M5B 1W8

Test Version

16-Nov-2022

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
VMARU 28004Creatinine Rand Urine mmol/L
28078VMA Random umol/L
28080VMA/Create Ratio Random umol/mmol cr

Test Version

16-Nov-2022