Test Overview
Clinical Utility
Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
Method
Enzyme Immunoassay (EIA)
Specimen
Specimen Type
SerumContainers
Collection Containers
SST (Gold Top)
Volume
Sample Volume
1 mL
Minimum Volume
0.3 mL
Patient Preparation
Overnight fasting preferred
Collection & Handling
Handling Information
Store and send cold or frozen.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 24 hours | 14 days | 30 days |
Performance & Interpretation
Turnaround Time
10 days
Results
Name
Units
Reference Range
Conversion
-
Histone AntibodiesU< 1.0 Negative
1.0 - 1.5 Weak Positive
1.6 - 2.5 Moderate Positive
> 2.5 Strong Positive
Referral Location
Out-of-Country
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| HISABQST S | HISTONE ANTIBODIES | 64650 | U |
Test Version
Last Updated
2022-09-29