Back to Test Catalogue

Voltage-gated Calcium Channel (VGCC) Antibodies by RIPA, Serum

Test ID: VGCCRIPA S

Test

Aliases/Synonyms

Lambert-Eaton Myasthenic Syndrome

Method

Radioimmunoprecipitation Assay

Report Includes

Voltage-gated Calcium Channel (VGCC) Antibodies

Specimens

Serum
Requisition: The specimen should be submitted with this ICL-BC Neurology requisition.
Billing Option: This test may be billed to the Medical Services Commission of BC - refer to Provincial Billing for eligibility and submission requirements.

Clinical Utility

Measuring VGCC antibodies is clinically useful in differentiating between neuromuscular disease and a polyneuritis. VGCC antibody-positivity should be followed by tumor investigation. If present, cancer treatment may improve symptoms of LEMS.

Test Location

BC Neuroimmunology Lab, Room S-157, 2211 Wesbrook Mall, Vancouver BC V6T 2B5

Test Version

15-Jun-2023

Specimen

Specimens

Serum
Requisition: The specimen should be submitted with this ICL-BC Neurology requisition.
Billing Option: This test may be billed to the Medical Services Commission of BC - refer to Provincial Billing for eligibility and submission requirements.

Collection Containers

Gold top (SST)

Sample Volume

5 mL

Minimum Volume

1 mL

Collection & Handling

Handling Information

Store and send frozen (preferred).

Stability

Refrigerated 7 days
Frozen 30 days

Additional Stability Information

If the specimen thaws, it is unsuitable for analysis.

Test Version

15-Jun-2023

Performance / Interpretation

Method

Radioimmunoprecipitation Assay

Turnaround Time

30 days

Results

Name Units Reference Range Conversion Factor
Voltage-gated Calcium Channel (VGCC) Antibodies by RIPA pmol/L
  • Negative: ≤ 30
  • Positive: > 30

Test Location

BC Neuroimmunology Lab, Room S-157, 2211 Wesbrook Mall, Vancouver BC V6T 2B5

Test Version

15-Jun-2023

Interface / Setup

Test Version

15-Jun-2023