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Desmoglein Antibodies 1 and 3, Serum

Test ID: DESM13 S

Test

Aliases/Synonyms

DSG 3; DSG 1; Pemphigus Foliaceus; Pemphigus Vulgaris

Method

ELISA

Report Includes

Desmoglein 1 Antibodies; Desmoglein 3 Antibodies

Specimens

Serum

Clinical Utility

To detect the presence of auto antibody specific to Desmoglein 1 and/or 3 in a patients serum as an aid to diagnose type of pemphigus

Test Location

Quest Diagnostics, California USA

Test Version

1-Mar-2023

Specimen

Specimens

Serum

Collection Containers

Gold top (SST)

Sample Volume

0.3 mL

Minimum Volume

0.1 mL

Patient Preparation

Fasting preferred

Collection & Handling

Collection Instructions

Blood should be collected fasting or at least one hour after meals to avoid lipemic serum

Handling Information

Allow the blood to clot at room temperature (20 to 25°C) and separate as soon as possible to limit hemolysis.

Stability

Ambient Unacceptable
Refrigerated 7 days
Frozen 28 days

Rejection Criteria

Hemolysis Gross
Lipemia Gross
Other Icteric, microbial growth
Specimen Heat inactivated or not frozen

Test Version

1-Mar-2023

Performance / Interpretation

Method

ELISA

Turnaround Time

11 days

Results

Name Units Reference Range Conversion Factor
Desmoglein 1 Antibodies U/mL
  • Negative: <14
  • Equivocal: 14 - 20
  • Positive: >20
Desmoglein 3 Antibodies U/mL
  • Negative: <9
  • Equivocal: 9 - 20
  • Positive: >20

Test Location

Quest Diagnostics, California USA

Test Version

1-Mar-2023

Interface / Setup

HL7 Interface Codes

Order Code Result Codes Units
DESM13 S 63346DESMOGLEIN 1 ANTIBODY U/mL
63347DESMOGLEIN 3 ANTIBODY U/mL

Test Version

1-Mar-2023