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Back to Test Catalogue
Test ID: NMRLP S

Lipoprotein Profile by Nuclear Magnetic Resonance (NMR), Serum

Orderable by Ontario ND

Test Overview

Clinical Utility

Assessment and management of a patient’s risk for atherosclerotic cardiovascular disease.
Identifying residual risk that may be present in some patients on cholesterol targeting treatment.

Method

Nuclear magnetic resonance spectroscopy (NMR)

Method Description

Lipoprotein particles are quantified in serum by nuclear magnetic resonance (NMR). The deconvoluting algorithm used is the AXINON Mayo LP Profiler software.(AXINON System User Manual Version 1.3.2, 3/2018)

Result Included

LDL Particles; HDL Particles; LDL Cholesterol (NMR), S

Aliases/Synonyms

Lipoprotein particles; LDL particle number; HDL particle number

Specimen

Specimen Type

Serum

Containers

Collection Containers

Red top (no additive)

Volume

Sample Volume

1.5 mL

Minimum Volume

1.0 mL

Patient Preparation

Fasting overnight (12 – 14 hours) is required. On night before examination, evening meal should be eaten before 6 p.m. and should contain no fatty foods.
Patient must not consume any alcohol for 24 hours before the specimen is collected.

Collection & Handling

Collection Instructions

Allow isopropyl alcohol (from phlebotomy site prep) to dry thoroughly before venipuncture.

Handling Information

Store and send frozen.

Stability

Ambient Refrigerated Frozen
8 hours 7 days 14 days

Rejection Criteria

Criteria Specification
Hemolysis Gross
Lipemia Gross
Other Grossly icteric

Performance & Interpretation

Turnaround Time

7 days

Results

Name
Units
Reference Range
Conversion
  1. LDL Particles
    nmol/L
    Desirable: <1000
    Above Desirable: 1000 - 1299
    Borderline high: 1300 - 1599
    High: 1600 - 2000
    Very high: ≥2000
  2. HDL Particles
    mcmol/L
    >30
  3. LDL Cholesterol (NMR)
    mg/dL
    Desirable: <100
    Above Desirable: 100 - 129
    Borderline high: 130 - 159 mg/dL
    High: 160 - 189 mg/dL
    Very high: ≥190

    Comment

    NMR LDL-C results compare to measured LDL-C but
    may be discrepant from estimated LDL-C values.

Referral Location

Out-of-Country

Interface & Setup

HL7 Interface Codes

Order Code Result Name Result Codes Units
NMRLP S LDL Particles, S 63205 nmol/L
HDL Particles, S 63206 mcmol/L
LDL Cholesterol (NMR), S 63207 mg/dL

Test Version

Last Updated

2020-12-01