Test Overview
Method
Liquid chromatography-mass spectrometry (LC-MS)
Result Included
Risperidone; 9-Hydroxyrisperidone; Risperidone + 9-Hydroxyrisperidone
Aliases/Synonyms
9-hydroxyrisperidone; paliperidone
Specimen
Specimen Type
Avoid gel separator tubesSerum
Plasma (Heparin)
Volume
Sample Volume
2 mL
Specimen Comment
Avoid gel separator tubes.
Collection & Handling
Collection Instructions
Collect trough specimen just prior to next dose or post-dose at a time ≥75% of the dosing interval.
Handling Information
Store and send frozen.
Performance & Interpretation
Turnaround Time
10 days
Results
Name
Units
Reference Range
Conversion
-
Risperidonenmol/L19.0 - 49.0ng/mL x 2.44
-
9-Hydroxyrisperidonenmol/L19.0 - 211.0ng/mL x 2.34
Comment
9-Hydroxyrisperidone (also known as Paliperidone) is an active metabolite of Risperidone. Please note that the therapeutic range for Paliperidone/9-Hydroxyrisperidone varies by whether patient is administered Paliperidone or Risperidone. The therapeutic range for patients administered Risperidone is displayed above.
-
Combined (Risperidone + 9-hydroxyrisperidone)nmol/LTherapeutic 19.0 - 260.0
Therapeutic ranges are valid for trough specimen collected just prior to next scheduled dose or post-dose at time ≥75% of the dosing interval
Referral Location
Canada
Test Version
Last Updated
2019-09-30