9-hydroxyrisperidone; paliperidone
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Risperidone and Metabolite, Serum/Plasma
Test ID: RISPER
Test
Aliases/Synonyms
Method
LC/MS
Report Includes
Risperidone; 9-Hydroxyrisperidone; Risperidone + 9-Hydroxyrisperidone
Specimens
Avoid gel separator tubes; Serum; Plasma (Heparin)
Test Location
Centre for Addiction and Mental Health, 100 Stokes Street, Toronto, ON M6J 1H4
Test Version
30-Sep-2019
Specimen
Specimens
Avoid gel separator tubes; Serum; Plasma (Heparin)
Sample Volume
2 mL
Specimen Comment
Avoid gel separator tubes.
Collection & Handling
Collection Instructions
Collect trough specimen just prior to next dose or post-dose at a time ≥75% of the dosing interval.
Handling Information
Store and send frozen.
Test Version
30-Sep-2019
Performance / Interpretation
Method
LC/MS
Turnaround Time
10 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Risperidone | nmol/L |
|
ng/mL x 2.44 | |
| 9-Hydroxyrisperidone | nmol/L |
|
ng/mL x 2.34 | |
|
9-Hydroxyrisperidone (also known as Paliperidone) is an active metabolite of Risperidone. Please note that the therapeutic range for Paliperidone/9-Hydroxyrisperidone varies by whether patient is administered Paliperidone or Risperidone. The therapeutic range for patients administered Risperidone is displayed above.
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| Combined (Risperidone + 9-hydroxyrisperidone) | nmol/L |
|
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Test Location
Centre for Addiction and Mental Health, 100 Stokes Street, Toronto, ON M6J 1H4
Test Version
30-Sep-2019
Interface / Setup
Test Version
30-Sep-2019