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Prealbumin, Serum

Test ID: PREALB

Test

Aliases/Synonyms

Transthyretin

Method

Turbidimetry

Report Includes

Prealbumin

Specimens

Serum

Clinical Utility

This test is used as a nutritional marker. Prealbumin is a transport protein for thyroxin synthesized in the liver. It has a half-life of 2 days, much shorter than that of albumin and is therefore a sensitive marker of nutritional status. Serum concentrations of prealbumin are not significantly affected by hydration status as is albumin. Like albumin, prealbumin is a negative acute phase reactant and its serum concentration decreases in inflammation, malignancy, liver cirrhosis and protein-losing diseases of the gut or kidneys.

Test Location

London Health Sciences Centre, 339 Windermere Road, London ON N6A 5A5

Test Version

30-Oct-2019

Specimen

Specimens

Serum

Sample Volume

1 mL

Minimum Volume

0.4 mL

Specimen Comment

Gel-separator tubes are acceptable.

Pediatric Volume

0 - 2 years: 0.5 mL Red top Microtainer; 2 - 10 years: 3 mL Red top Vacutainer tube

Pediatric Minimum

0.15 mL

Collection & Handling

Collection Instructions

Fasting collection is recommended. Do not use chlorhexidine antiseptic swab to cleanse the skin, use an alcohol swab.

Handling Information

Separate serum from cells within 2 hours. Store and send frozen.

Stability

Refrigerated 3 days
Frozen 6 months

Test Version

30-Oct-2019

Performance / Interpretation

Method

Turbidimetry

Turnaround Time

2 days

Results

Name Units Reference Range Conversion Factor
Prealbumin g/L
  • Adult: 0.20 - 0.40
  • 0 - <15 d: 0.00 - 0.11
  • 15 days - <1 y: 0.04 - 0.24
  • 1 - <5 y: 0.11 - 0.23
  • 5 - <13 y: 0.13 - 0.26
  • 13 - <16 y: 0.17 - 0.31
  • F, 16 - <19 y: 0.16 - 0.33
  • M, 16 - <19 y: 0.20 - 0.35

Test Location

London Health Sciences Centre, 339 Windermere Road, London ON N6A 5A5

Test Version

30-Oct-2019

Interface / Setup

Test Version

30-Oct-2019