Uroporphyrin I; Uroporphyrin III; Heptacarboxylic Acid; Hexacarboxylic Acid; Pentacarboxylic; Coproporphyrin I; Coproporphyrin III; Copro III/Copro I; Interpretation
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Porphyrins Quantitation, 24 hr Urine
Test ID: PORPHQ U
Test
Method
HPLC
Report Includes
Specimens
Urine (24 hr)
Clinical Utility
Quantitation may only be done if a preliminary screen (billed separately) is positive.
Test Version
3-Sep-2025
Specimen
Specimens
Urine (24 hr)
Sample Volume
20 mL
Specimen Comment
This collection is not suitable for ALA/PBG testing.
Collection & Handling
Collection Instructions
Collect 24 hour urine with 5 g sodium carbonate. Protect from light – collect in dark bottle. Keep cool during collection.
Handling Information
Final pH should be 7 to 10. Indicate volume (in litres) and collection date. Store and send frozen.
Test Version
3-Sep-2025
Performance / Interpretation
Method
HPLC
Turnaround Time
8 days
Results
| Name | Units | Reference Range | Conversion Factor | |
|---|---|---|---|---|
| Uroporphyrin I | nmol/d |
|
||
| Uroporphyrin III - U (24 hr) | nmol/d |
|
µg/24 hr x 1.20 | |
| Heptacarboxylic Acid | nmol/d |
|
||
| Hexacarboxylic Acid | nmol/d |
|
||
| Pentacarboxylic | nmol/d |
|
||
| Coproporphyrin I | nmol/d |
|
µg/24 hr x 1.53 | |
| Coproporphyrin III | nmol/d |
|
µg/24 hr x 1.53 | |
| Copro III/Copro I | Ratio |
|
||
|
Porphyrin reference values are not available for individuals 17 y and younger.
|
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|
|
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Test Version
3-Sep-2025
Interface / Setup
HL7 Interface Codes
| Order Code | Result Codes | Units |
|---|---|---|
| PORPHQ U | 66218Uroporphyrin I 24h/Timed Urine | nmol/d |
| 20263Uroporphyrin III 24h Urine | nmol/d | |
| 20264Heptacarboxylic Acid Porph 24h Urine | nmol/d | |
| 20265Hexacarboxylic Acid Porph 24h Urine | nmol/d | |
| 20266Pentacarboxylic Acid Porph 24h Urine | nmol/d | |
| 20267Coproporphyrin I 24h Urine | nmol/d | |
| 20268Coproporphyrin III 24h Urine | nmol/d | |
| 20269Copro III:Copro I 24h | Ratio | |
| 20270Interpretation |
Test Version
3-Sep-2025