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Platelet Antibodies Indirect IgG + IgM, Serum

Test ID: PLAB S

Test

Method

Flow Cytometry

Report Includes

Platelet Antibodies Indirect IgG; Platelet Antibodies Indirect IgM

Specimens

Serum

Clinical Utility

The identification of circulating platelet antibodies is useful in order to identify immune-mediated platelet destruction. Disorders associated with immune platelet destruction include isoimmune neonatal thrombocytopenia, drug induced thrombocytopenia, drug sensitivities, allergies and post transfusion purpura. The destruction is either congenital, i.e., autoimmune where a malfunction in the immune response results in the production of antibodies directed against 'self' platelet specific antigens; or else platelet destruction occurs when the patient received platelet-specific antibodies from an outside source such as a non-compatible blood transfusion or maternal transfer across the placental barrier. In either of the above situations, the detection of platelet antibodies is useful in order to determine if an immune basis is responsible for the thrombocytopenia observed clinically.

https://testdirectory.questdiagnostics.com/test/test-detail/91744/platelet-antibodies-indirect-igg-igm?p=r&q=Platelet%20Antibodies,%20Indirect%20(IgG,%20IgM)&cc=MASTER; Accessed 12-Jun-2019

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Specimen

Specimens

Serum

Sample Volume

2 mL

Minimum Volume

1 mL

Collection & Handling

Handling Information

Store and send cold.

Stability

Ambient Unacceptable
Refrigerated 21 days
Frozen Unacceptable

Rejection Criteria

Hemolysis Present
Lipemia Present
Other Icteric

Test Version

30-Sep-2019

Performance / Interpretation

Method

Flow Cytometry

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
Platelet Antibodies Indirect IgG
  • Negative
Platelet Antibody Indirect IgM
  • Negative

Test Location

Quest Diagnostics, California USA

Test Version

30-Sep-2019

Interface / Setup

Test Version

30-Sep-2019