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Back to Test Catalogue
Test ID: NSE S

Neuron Specific Enolase (NSE), Serum

Test Overview

Clinical Utility

Elevated levels of serum NSE are reported in patients with small cell carcinomas primarily of lung origin. Patients with neuroblastomas may
also have high levels of NSE. Serum NSE can be used to monitor recurrence or progression of tumor in these cancer patients. Daily serial
monitoring of serum NSE may also be used in comatose patients to assess neuronal damage. High NSE levels in comatose patients at 24
and 48 hours post cardio-pulmonary resuscitation have been associated with poor outcome. Hemolysis can cause false positive results.

Method

Enzyme Immunoassay (EIA)

Result Included

Neuron Specific Enolase (NSE)

Specimen

Specimen Type

Serum

Volume

Sample Volume

1 mL

Minimum Volume

0.3 mL

Collection & Handling

Handling Information

Store and send refrigerated.

Stability

Ambient Refrigerated Frozen
7 days 7 days 30 days

Performance & Interpretation

Turnaround Time

6 days

Results

Name
Units
Reference Range
Conversion
  1. Neuron Specific Enolase
    ng/mL
    ≤ 14

Referral Location

Out-of-Country

Test Version

Last Updated

2022-08-25