Test ID: PORPHQRU

Porphyrins Quantitation, Random Urine

Test Overview

Clinical Utility

Quantitation may only be done if a preliminary screen is positive.

Method

High Performance Liquid Chromatography (HPLC)

Result Included

Creatinine; Uroporphyrin I; Uroporphyrin III; Heptacarboxylic Acid; Hexacarboxylic Acid; Pentacarboxylic Acid; Coproporphyrin I; Coproporphyrin III; Copro III/Copro I Ratio; Interpretation

Specimen

Specimen Type

Urine (Random)

Volume

Sample Volume

20 mL

Specimen Comment

This collection is not suitable for PBG/ALA analysis.

Collection & Handling

Handling Information

pH should be adjusted with sodium carbonate immediately following collection. Final pH should be 7 to 10.
Store and submit specimen protected from light.
Store and send frozen.

Additional Information

Indicate random collection and collection date.

Rejection Criteria

Criteria	Specification
Specimen	Not protected from light

Performance & Interpretation

Turnaround Time

8 days

Results

Creatinine

mmol/L

Not available for random urine
Uroporphyrin I

nmol/mmol cr

0.4 - 3.9
Uroporphyrin III

nmol/mmol cr

Adult: ≤2.0
Heptacarboxylic Acid

nmol/mmol cr

Adult: ≤1.3
Hexacarboxylic Acid

nmol/mmol Cr

≤0.7
Pentacarboxylic Acid

nmol/mmol cr

Adult: ≤1.0
Coproporphyrin I

nmol/mmol cr

Adult: 0.3 - 8.5
Coproporphyrin III

nmol/mmol cr

Adult: 1.7 - 26.3
Copro III/Copro I Ratio

Ratio

Adult: 2.6 - 5.3
Interpretation

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code	Result Name	Result Codes	Units
PORPHQRU	Uroporphyrin I:Creatinine Ratio Random Urine	66219	nmol/mmol Cr
	U. Uroporphyrin III	20788	nmol/mmol Cr
	U. Heptacarboxylic Acid	20789	nmol/mmol Cr
	U. Hexacarboxylic Acid	20790	nmol/mmol Cr
	U. Pentacarboxylic Acid	20791	nmol/mmol Cr
	U. Coproporphyrin I	20792	nmol/mmol Cr
	U. Coproporphyrin III	20793	nmol/mmol Cr
	U. Copro III/I Ratio	20794	Ratio
	Interpretation	20795
	Creatinine Random Urine	20786	mmol/L

Test Version

Last Updated

2025-09-03