Test Overview
Method
Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Result Included
Amiodarone; Desethylamiodarone
Specimen
Specimen Type
Avoid gel separator tubesSerum
Volume
Sample Volume
3 mL
Minimum Volume
1.0 mL
Specimen Comment
Avoid gel separator tubes.
Collection & Handling
Collection Instructions
To monitor therapy, draw trough specimen prior to next dose.
Handling Information
Store and send frozen.
Stability
| Refrigerated | Frozen |
|---|---|
| 72 hours | 2 Years (-70°C) |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Gel-separator tube |
Performance & Interpretation
Turnaround Time
7 days
Results
Name
Units
Reference Range
Conversion
-
Amiodaronemg/L1.0 - 2.0
Toxic: > 2.0
Comment
Effective October 17, 2024, a calibration adjustment will result in an average decrease of 0.25mg/L in serum amiodarone and metabolite values.
-
Desethylamiodaronemg/LNo Therapeutic range established.
Comment
Effective October 17, 2024, a calibration adjustment will result in an average decrease of 0.25mg/L in serum amiodarone and metabolite values.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| AMIO | Amiodarone | 2541 | mg/L |
| Desethylamiodarone | 28342 | Desethylamiodarone | |
| Test Comment | 40002 |
Test Version
Last Updated
2024-10-18