Test Overview
Clinical Utility
Lactate dehydrogenase (LD) is present in many different organs and tissues such as liver, heart, muscles, kidney, lungs and blood. The usual designation of isoenzymes is LD-I, LD-II, LD-III, LD-IV and LD-V. LD isoenzymes tissue specificity is derived from the fact that LD subunits are synthesized in well-defined ratios and could be used in investigating unexplained causes of Total LD elevations and detection of macro-LD. Do not use LD isoenzymes to detect myocardial injury.
Method
Electrophoresis - spectrophotometry
Result Included
Lactate Dehydrogenase (LD); Lactate Dehydrogenase Isoenzymes LD1; LD2; LD3; LD4; LD5
Specimen
Specimen Type
SerumContainers
Collection Containers
Gold top (clot activator & gel)
Volume
Sample Volume
2 mL
Minimum Volume
1 mL
Collection & Handling
Handling Information
Separate within 1 hour of collection. Do not refrigerate or freeze the specimens. Store and send at ambient temperature.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 7 days | Unacceptable | Unacceptable |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Hemolysis | Present |
| Specimen | Received refrigerated or frozen |
Performance & Interpretation
Turnaround Time
10 days
Results
-
LDU/LMale
< 1 Month: 125 -735
1 - 11 Months: 170 - 450
1 - 3 Years: 155 - 345
4 - 6 Years: 155 - 345
7 - 10 Years: 140 - 270
11 - 13 Years: 110 - 250
14 - 17 Years: 110 - 230
18 - 49 Years: 100 - 220
> 49 Years: 120 - 250
Female
< 1 Month: 145 - 765
1 - 11 Months: 190 - 420
1 - 3 Years: 165 - 395
4 - 6 Years: 135 - 345
7 - 10 Years: 140 - 270
11 - 13 Years: 110 - 250
14 - 17 Years: 110 - 230
18 - 49 Years: 100 - 200
> 49 Years: 120 - 250 -
LD1%18 - 32
-
LD2%29 - 42
-
LD3%14 - 30
-
LD4%6 - 13
-
LD5%5 - 18
Referral Location
Out-of-Country
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| LDISOENZP S | LD | 65324 | U/L |
| LD1 | 65325 | % | |
| LD2 | 65326 | % | |
| LD3 | 65327 | % | |
| LD4 | 65328 | % | |
| LD5 | 65329 | % |
Test Version
Last Updated
2024-01-19