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Test ID:
COLCLNPEP U
Collagen Cross-Linked N-Telopeptide (NTx), Random Urine
Test Overview
Clinical Utility
NTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss. A decline of 30% or more of NTx over a six-month period suggests effective therapy.
Method
Chemiluminescence (CL)
Result Included
N-Telopeptide; Creatinine
Aliases/Synonyms
Ntelopeptide
Specimen
Specimen Type
UrineContainers
Collection Containers
Sterile Container
Volume
Sample Volume
2 mL
Minimum Volume
1 mL
Collection & Handling
Collection Instructions
Second morning void urine: Discard the first morning void. Collect the second morning void. Mix well. Do not use preservatives. Acidified specimen is not acceptable.
Handling Information
Store and send frozen.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 3 days | 5 days | 30 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Preservative |
Performance & Interpretation
Turnaround Time
8 days
Results
Name
Units
Reference Range
Conversion
-
N-Telopeptide, Random UrinenM BCE/mM creatMale:
18 y - 29 y: 12 - 99
30 y - 59 y: 9 - 60
Female:
Premenopausal: 4 - 64
Comment
Results are primarily used for monitoring the response to therapy. A value within the premenopausal reference range does not rule out osteoporosis nor the need for therapy.
-
Creatine, Random Urinemg/dL≤ 6 months: 2 - 28
7 - 11 months: 2 -31
1 y - 2 y: 2 - 110
3 y - 8 y: 2 - 130
9 y - 12 y: 2 - 160
> 12 y (Male): 20 - 320
> 12 y (Female): 20 - 275
Referral Location
Out-of-Country
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| COLCLNPEP U | N-Telopeptide (NTx) | 65186 | nM BCE/mM creat |
| Creatinine, Random Urine | 65187 | mg/dl |
Test Version
Last Updated
2023-08-18