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Back to Test Catalogue
Test ID: BENCEJ

Bence-Jones Protein (IFE) and Reflex Protein Electrophoresis, Urine

Test Overview

Clinical Utility

Urine Bence-Jones (BJ) by immunofixation is more specific for Bence-Jones proteins than protein electrophoresis (PE).
Eliminating initial PE screening enables shorter laboratory turnaround time and faster final reports.
Quantitating detected BJ proteins allows longitudinal monitoring, rather than merely indicating their presence or absence.

Method

Immunofixation Electrophoresis (IFE)

Result Included

Free Kappa Light Chains; Free Lambda Light Chains; Protein; Albumin; Alpha-1 Globulin; Alpha-2 Globulin; Beta Globulin; Gamma Globulin; M-Spike

Aliases/Synonyms

UBJ; UPE; Bence Jones protein

Specimen

Specimen Type

Random Urine
24h Urine

Volume

Sample Volume

15 mL

Minimum Volume

10 mL

Collection & Handling

Collection Instructions

Submit an aliquot of a random collection (first morning void preferred) or an aliquot of a 24-hour preservative-free urine collection.

Handling Information

Store and send frozen.

Additional Information

If Bence-Jones proteins are detected, protein electrophoresis will be performed, reported and billed.

Stability

Ambient Refrigerated Frozen
7 days 30 days 180 days

Rejection Criteria

Criteria Specification
Other Preservatives

Performance & Interpretation

Turnaround Time

8 days

Results

Name
Units
Reference Range
Conversion
  1. Free Kappa Light Chains
    Qualitative Test
    Absent
  2. Free Lambda Light Chain
    Qualitative Test
    Absent
  3. Urine Protein
    g/L
    0.00 - 0.10
  4. Total Volume
    L
  5. Albumin
    %

    Comment

    Reported when protein electrophoresis is performed.

  6. Alpha-1 Globulins
    %

    Comment

    Reported when protein electrophoresis is performed.

  7. Alpha-2 Globulins
    %

    Comment

    Reported when protein electrophoresis is performed.

  8. Beta Globulins
    %

    Comment

    Reported when protein electrophoresis is performed.

  9. Gamma Globulins
    %

    Comment

    Reported when protein electrophoresis is performed.

  10. M-Spike
    %
    Not detected

    Comment

    Reported when protein electrophoresis is performed.

  11. Interpretation

    Comment

    Quantitative estimation of Bence-Jones protein is reported when protein electrophoresis is performed.
    24 hour Urine: Bence-Jones protein is reported as both percentage of total protein and absolute quantity (g/d and/or g/L).
    Random Urine: Bence-Jones protein is reported as the percentage of total protein.

Referral Location

Canada

Interface & Setup

HL7 Interface Codes

Order Code Result Name Result Codes Units
Multiple HL7 codes 0

Test Version

Last Updated

2023-08-08