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Test ID:
ESTDFREE S
Estradiol – Free, Serum
Orderable by Ontario ND
Test Overview
Clinical Utility
Much of Estradiol is bound to proteins. The unbound portion and Estradiol bound to proteins with low affinity reflect the free concentration. The Free Estradiol may better correlate with medical conditions than the Total Estradiol concentrations.
Method
Liquid chromatography-mass spectrometry (LC-MS) and Equilibrium Dialysis
Result Included
Estradiol, Free; Estradiol
Specimen
Specimen Type
Avoid gel-separator tubesSerum
Containers
Collection Containers
Red top (no additive)
Volume
Sample Volume
1 mL
Minimum Volume
0.5 mL
Specimen Comment
Avoid gel-separator tubes.
Collection & Handling
Handling Information
Store and send frozen.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 24 hours | 7 days | 28 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Hemolysis | Gross |
| Lipemia | Gross |
| Icterus | Gross |
| Specimen | Gel separator tubes |
Performance & Interpretation
Turnaround Time
16 days
Results
Name
Units
Reference Range
Conversion
-
Estradiol, Freepg/mLAdults: ≤ 0.45
-
Estradiolpg/mL≤ 29
Referral Location
Out-of-Country
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| ESTDFREE S | ESTRADIOL, FREE | 64727 | pg/mL |
| ESTRADIOL | 64728 | pg/mL |
Test Version
Last Updated
2023-01-13