Test Overview
Clinical Utility
This ImmunoCAP Allergen Component test measures IgE antibodies specific to individual molecular allergens. These allergens, which are purified or recombinant proteins, offer the unique opportunity to assess a persons allergic sensitization pattern.
Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Analytical Platform
Phadia
Method Description
ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.
Result Included
Cat rFel d 4 (e228) IgE
Specimen
Specimen Type
SerumContainers
Collection Containers
Gold top (clot activator & gel)
Volume
Sample Volume
1 mL
Minimum Volume
50 uL
Specimen Comment
Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.
Collection & Handling
Handling Information
Store and send frozen
Additional Information
Refer to the list of available IgE Allergen Tests.
Stability
| Refrigerated | Frozen |
|---|---|
| 3 days | 6 months |
Performance & Interpretation
Turnaround Time
10 days
Results
-
Cat rFel d 4 (e228) IgEkU/L<0.35
Comment
Approximately 60% of cat allergic subjects have IgE antibodies to this component molecule often at low IgE levels
Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of asymptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Use caution when interpreting drug, venom and potential anaphylactic allergen results.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| FELD4 | ALLERGEN ANIMAL: RFEL D 4 CAT IGE (KU/L) E228 | 62423 | kU/L |
Test Version
Last Updated
2023-11-17