Cytokine Panel 1 (IL-10, IL-18, IL-1B, IL-6), Plasma
Test Overview
Method
Fluorescence immunoassay (FIA)
Analytical Platform
Proteinsimple ELLA<br>This analysis is performed at Hospital for Sick Children, Toronto, ON, CA
Result Included
Interleukin 10 (IL-10); Interleukin 18 (IL-18); Interleukin 1 beta (IL-1B); Interleukin 6;
The four tests included in this profile may be ordered individually.
The price for any of these four tests ordered individually is the same as the price for the four-test profile.
Interleukin 10 (IL-10), Plasma
Interleukin 18 (IL-18), Plasma
Interleukin 1 beta (IL-1B), Plasma
Interleukin 6 (IL-6), Plasma
Aliases/Synonyms
Interleukin-10; IL10; Interleukin-18; IL18; Interleukin-1beta; IL1b; Interleukin-6
Specimen
Specimen Type
Plasma (EDTA)Containers
Collection Containers
Lavender top (EDTA)
Volume
Sample Volume
0.5 mL x 2
Minimum Volume
0.25 mL x 2
Collection & Handling
Handling Information
Separate within 30 minutes of collection. Centrifuge for 15 minutes at 1000 RCF. Prepare two 0.5 mL aliquots (min 2 x 0.25 mL). Store and ship frozen.
Additional Information
Avoid freeze-thaw cycles
Stability
| Ambient |
|---|
| Unacceptable |
Avoid freeze-thaw cycles
Rejection Criteria
| Criteria | Specification |
|---|---|
| Hemolysis | Gross |
| Lipemia | Gross |
Performance & Interpretation
Turnaround Time
14 days
Results
-
Interleukin 10 (IL-10)pg/mL≤4.2
-
Interleukin 18 (IL-18)pg/mL≤266
-
Interleukin 1 beta (IL-1B)pg/mL≤1.0
-
Interleukin-6pg/mL≤3.7
Comment
Results should be interpreted in the context of the clinical presentation, therapeutic intervention, and additional laboratory data. Assay performance has not been validated in the context of treatment monitoring following administration of cytokine-blocking therapies; interpret results in this context with caution.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| CYTOONE P | Interleukin-10 | 64282 | pg/mL |
| Interleukin-18 | 64283 | pg/mL | |
| Interleukin-1b | 64284 | pg/mL | |
| Interleukin-6 | 64285 | pg/mL | |
| Cytokine 1 Comment | 64442 |
Test Version
Last Updated
2022-06-23