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Test ID:
METFRU
Metanephrines – Fractionated LC-MS/MS, Random Urine
Test Overview
Method
Liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Result Included
Free Normetanephrine; Free Normetanephrine/Creatinine Ratio; Free Metanephrine; Free Metanephrine/Creatinine Ratio; 3-Methoxytyramine; 3-Methoxytyramine/Creatinine Ratio; Creatinine
Aliases/Synonyms
Fractionated Metanephrines, Metanephrines Free, urine, NMN, urine, Normetanephrine, free, Normetanephrines, urine
Specimen
Specimen Type
Urine (Random)Volume
Sample Volume
25 mL
Patient Preparation
Restrict caffeine, nicotine and alcohol for 24 hours prior to collection. Discontinue Methyldopa (Aldomet) at least 5 days prior to collection. Avoid reserpine, alpha methyldopa, levodopa, monoamine oxidase inhibitors.
Collection & Handling
Handling Information
Acidify aliquot with 6 mol/L (6N) HCl. The final pH of the urine must be 2.0 – 4.0.
Stability
| Refrigerated | Frozen |
|---|---|
| 1 month | >1 month |
Performance & Interpretation
Turnaround Time
10 days
Results
Name
Units
Reference Range
Conversion
-
Creatininenmol/L
-
Free Normetanephrinenmol/L
-
Free Normetanephrine/Creatinine Rationmol/mmol creatinine
-
Free Metanephrinenmol/L
-
Free Metanephrine/Creatinine Rationmol/mmol creatinine<31
-
3-Methoxytyraminenmol/L
-
3-Methoxytyramine/Creatinine Rationmol/mmol creatinine<45.0
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| METFRU | Normetanephrine Random Free | 63304 | nmol/L |
| Normet/Crt Ratio | 63305 | nmol/mmol creat | |
| Metanephrine Random Free | 63306 | nmol/L | |
| Met/Crt Ratio | 63307 | nmol/mmol creat | |
| Methoxytyramine Random | 63308 | nmol/L | |
| 3-Methoxytyramine/Creat Ratio | 63309 | nmol/mmol creat | |
| Creatinine Rand Urine | 28004 | mmol/L |
Test Version
Last Updated
2023-12-21