Wheat (f4) IgE, Serum
Orderable by Ontario ND
Test Overview
Clinical Utility
In patients suffering from extrinsic asthma, hay fever or atopic eczema, symptoms develop after exposure to specific allergens. This immediate (atopic or anaphylactic) type of allergy is a function of a special type of serum antibodies belonging to the IgE class of immunoglobulins.
Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Analytical Platform
Phadia
Method Description
ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.
Result Included
Wheat (f4) IgE
Specimen
Specimen Type
SerumVolume
Sample Volume
1 mL
Specimen Comment
Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.
Collection & Handling
Handling Information
Store and send frozen.
Additional Information
Refer to the list of available IgE Allergen Tests.
Stability
| Refrigerated | Frozen |
|---|---|
| 3 days | 6 Months |
Performance & Interpretation
Turnaround Time
10 days
Results
-
Wheat (f4), IgEKU/L<0.35
Comment
Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approximately 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.
Use caution when interpreting drug, venom and potential anaphylactic allergen results.
Interpretive Comment: Storage protein (2S albumin). Heat and digestion stable. Highly abundant in cashew nut. Associated with systemic reactions.
Referral Location
Canada
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| WHEAT | IgE Wheat | 31044 | kU/L |
Test Version
Last Updated
2023-11-17