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Test ID:
TSIQST
Thyroid Stimulating Immunoglobulin (TSI) Bioassay, Serum
Test Overview
Clinical Utility
Graves’ disease is a classic form of hyperthyroid disease. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.
Method
Bioassay
Result Included
Thyroid Stimulating Immunoglobulin (TSI)
Specimen
Specimen Type
SerumContainers
Collection Containers
Gold top (clot activator & gel)
Volume
Sample Volume
1.0 mL
Minimum Volume
0.2 mL
Collection & Handling
Handling Information
Store and send cold or frozen.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| Unacceptable | 21 days | 60 days |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Plasma |
| Hemolysis | Gross |
| Lipemia | Gross |
| Icteric | Gross |
Performance & Interpretation
Turnaround Time
9 days
Results
Name
Units
Reference Range
Conversion
-
TSI% Baseline<140
Referral Location
Out-of-Country
Interface & Setup
HL7 Interface Codes
| Order Code | Result Name | Result Codes | Units |
|---|---|---|---|
| TSIQST | TSI | 38472 | % baseline |
Test Version
Last Updated
2023-05-09