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Test ID:
THIORQST
Thioridazine and Metabolite, Serum/Plasma
Test Overview
Clinical Utility
Thioridazine is a phenothiazine for treating psychosis. Monitoring its level is important to optimize therapy, to avoid toxicity, and to assure compliance.
https://testdirectory.questdiagnostics.com/test/test-detail/23232/thioridazine-and-metabolite?q=23232&cc=MET, Accessed 12-Jun-2019.
Method
Gas Chromatography (GC)
Result Included
Thioridazine; Mesoridazine
Aliases/Synonyms
Mellaril®
Specimen
Specimen Type
Avoid gel separator tubesSerum
Plasma (EDTA)
Volume
Sample Volume
2 mL
Minimum Volume
0.7 mL
Specimen Comment
Avoid gel separator tubes.
Stability
| Ambient | Refrigerated | Frozen |
|---|---|---|
| 8 days | 8 days | 1 Year |
Rejection Criteria
| Criteria | Specification |
|---|---|
| Specimen | Gel-separator tube |
Performance & Interpretation
Turnaround Time
10 days
Results
Name
Units
Reference Range
Conversion
-
Thioridazineng/mLSee note below
Comment
Steady-state serum concentration during chronic oral administration of 400 mg daily: 140 - 2600 ng/mL.
Therapeutic steady-state concentrations may overlap levels associated with toxicity.
-
Mesoridazineng/mLTherapeutic range: 100 - 1400
Referral Location
Out-of-Country
Test Version
Last Updated
2019-09-30